New Opioid Receptor Modulators and Agonists - Relevance for Pain and Opioid Use Disorder Management

New Opioid Receptor Modulators and Agonists: Relevance for Pain and Opioid Use Disorder Management provides crucial insights for developing ideal synthetic opioids. It discusses opioid receptor modulators’ structures and mechanisms, and their potential applications in treating pain, misuse, and addiction. This comprehensive resource delves into current research and therapeutic development avenues regarding opioid receptors' structure and function. Sections cover the rationale for developing allosteric modulators, identifying allosteric sites on opioid receptors, and the modulators' modes of action. Readers will gain a thorough understanding of creating ideal synthetic opioids and potential future research. It also explores pharmacogenomics, precision medicine, and various syndromes and comorbidities linked to opioid use. Lastly, it reviews novel synthetic opioids and the risks of misuse and overdose.