Brain Energy Metabolism in Alzheimer’s Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer’s disease and related disorders. Chapters in this release examine metabolic therapeutic targets in Alzheimer’s disease, alterations in brain energy metabolism in comparison with Parkinson’s disease, and the role of epigenetic modulation through natural compounds. Additional sections address mitochondrial dysfunction, disruption of metabolic pathways, and the contribution of glial cells to neurodegenerative processes. Further contributions explore metabolic disorders linked to Parkinson’s disease, signaling pathways in neurodegeneration, and advances in therapeutic and diagnostic strategies targeting key enzymes. The volume also highlights the role of intestinal microbiota, nanocarrier-based therapeutic approaches, and emerging treatments such as HDAC inhibitors. Together, these chapters provide a comprehensive overview of the mechanisms, biomarkers, and therapeutic prospects related to energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.
