Introducing the principles of rational drug design, including novel and
established approaches, this updated edition includes advances in molecular
techniques, biotechnological applications and computer-aided design.As knowledge of biological systems has expanded and the number of
techniques available for exploring and visualizing their components has
increased, it has become possible to design drugs specifically for a given
target. This unique insight has revolutionized the process of drug development
for specific disease states. Smith and Williams' Introduction to the Principles
of Drug Design and Action, 4th Edition provides a thorough introduction to the
principles of rational drug design, including both novel and established
approaches. The fourth edition of this popular textbook adopts a 'from the
bench to the marketplace' approach, using real examples where possible. In
addition to a comprehensive update of the previous edition, new advances in
molecular techniques, biotechnological applications and computer-aided design
have been added.