The cult of relics, encouraged by, among others, the emperor Constantine, Pope Damasus and the bishops Ambrose of Milan and Paulinus of Nola, led to the transformation of the Late Antique Italian landscape, and of suburban areas in particular. The process of gradual enhancement of the martyrs'' tombs led to the creation of extensive sanctuaries, generally composed of funerary and cultic buildings, as well as service structures, pilgrims'' lodgings and monasteries. The most important sanctuaries, such as those of Saints Peter in the Vatican, Paul on the Ostiense, Erasmus in Formia, Alexander in Nomentum, Felix in Cimitile, Gennaro in Naples, Felix in Venosa, Marcianus in Syracuse, and the Apostles in Concordia Sagittaria, became so popular that they justified Jerome''s phrase: movetur urbs sedibus suis et currit ad martyrum tumulos. Between the 5th and 6th century, sanctuaries spread also in rural areas, usually along important roads, as documented by the site of San Canzian d''Isonzo. Analysing hypogeal and subdial contexts, Santuari e spazi confessionali nell’Italia tardoantica outlines the evolution of loca sancta, in a process that led the venerated tombs to become first memoriae, then places of worship and finally articulated sanctuaries. For the first time, the contexts of Rome are organically compared with those of the rest of Italy.
