This handbook provides a comprehensive overview of the application of nanotechnology in agricultural sectors to boost sustainable agriculture with the use of these modern age nanomaterials and nanodevices that are empowering to attain maximum output from limited resources. The application of nanotechnology includes, enhancing plant growth and protection through the use of nanoparticles, the management of plant diseases and pest management through nano herbicides nanofungicides, nano/smart fertilizers for controlled and target release of nutrients, food processing and preservation with polymers nanocomposites. Further, in agriculture sectors nanosensors seem to be a promising tool for detection of fertilizers, herbicides, pesticides, and insecticides as well as pathogens, moisture, soil pH, soil contaminants, contaminants, and other parameters to improve crop health and sustainability. Moreover, nanosensors have also a significant role in precision agriculture activity, satellite farming or site-specific crop plants management in terms of detecting, calculating, and responding to inter and intra-field variability of crop plants. This handbook summarizes the recent findings, in-depth discussions and a wide range applications associated with smart nano research and technology for overall agricultural sectors and represents an indispensable reference for nano-based professionals, academic researchers, and upper level of students.