This book explores central aspects of genetic modification of animals for scientific purposes in the context technological possibilities, regulatory issues in different regions, animal welfare implications and wider ethical issues, exemplified through current theories and frameworks.
This discussion of lab animals produced through modern biotechnologies becomes increasingly pressing as CRISPR-Cas9 technology advances rapidly, challenging legal and ethical frameworks all over the world. Such animals are now affordable and readily available to almost every branch of scientific research. This raises enormous potential for creating -tailored- models for human diseases but also rubs up against the traditional guiding principles (the 3Rs) for the humane use of animals for scientific experiments and raises wider ethical issues around death, integrity, and naturalness. In this book, expert authors from diverse backgrounds in laboratory animal care, animal research, technology and anim
