This volume provides a comprehensive and interdisciplinary examination of contemporary coffee science, integrating genomics, biochemistry, analytical chemistry, nanotechnology, sustainability, and human health. It explores the genetic diversity and conservation of Coffea species, highlighting recent advances in genome sequencing, mapping technologies, and data-driven breeding strategies aimed at improving climate resilience, productivity, and quality. The biochemical complexity of coffee beans is critically addressed, with emphasis on key constituents such as caffeine, chlorogenic acids, diterpenes, trigonelline, and Maillard reaction products. Advanced chromatographic and mass spectrometric techniques used for the characterization, authentication, and quality control of coffee bioactive are systematically reviewed. The volume further examines the pharmacological and molecular effects of coffee consumption, incorporating evidence from human genetics, multi-omics research, and clinical studies to explain interindividual variability in health outcomes. A central focus is placed on sustainability and innovation, including the valorisation of coffee by-products within circular bioeconomy frameworks and the development of coffee-derived nanomaterials for biomedical, environmental, and technological applications, alongside critical safety and toxicological considerations. This book is intended for researchers, biochemists, plant scientists, food technologists, and professionals working in the coffee and nanotechnology industries.
