In this issue of Clinics in Laboratory Medicine, guest editors Drs. Christine Snozek and Adina Badea bring their considerable expertise to the topic of Update on Therapeutic Drug Monitoring. Top experts provide current information on therapeutic drug monitoring (TDM) for a variety of drugs and patient populations, along with practical considerations for laboratories performing TDM. Articles cover key topics such as special populations for whom TDM is both essential and challenging, including pediatrics, pregnant women, and patients with organ dysfunction; novel angles on classic drugs such as immunosuppressants and psychoactives; newer TDM targets including monoclonal antibody therapies; and a wide variety of practical considerations. Contains 12 relevant, practice-oriented topics including TDM considerations in pregnancy; the clinical potential for TDM in alternative matrices: considerations for systemic and compartmentalized pharmacology; TDM of immunosuppressants in cardiac transplantation; playing devil’s advocate: why not to do TDM; and more. Provides in-depth clinical reviews on therapeutic drug monitoring, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
